BIOL 76 Advanced Genetics

Methods and strategies for the analysis of gene structure, function and genetic interactions. The course will examine how the genetic manipulation of model organisms, including yeast, Drosophila, C. elegans, and mouse, is used to explore the mechanisms of fundamental biological processes such as cell division, development, and intercellular communication. Emphasis will be placed on the application of classical genetic methods, including mutant screens, recombination and complementation analysis, genetic mosaics, and the use of conditional mutations. Modern molecular-based approaches, including gene knockout, gene dosage and misexpression studies will also be included. Three hours of lecture and one hour of discussion per week.

Instructor

McClung

Prerequisite

BIOL 12/BIOL 19 and BIOL 13 and one from among BIOL 40, BIOL 41, BIOL 43, BIOL 45, BIOL 47, CHEM 41 or instructor permission

Degree Requirement Attributes

Dist:SCI

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Offered

• Fall